{"product_id":"kisspeptin-10","title":"KissPeptin-10","description":"\u003cdiv class=\"markdown markdown-main-panel md-content enable-updated-hr-color force-compact-layout stronger tutor-markdown-rendering\" id=\"model-response-message-contentr_397d5f728215f58d\" dir=\"ltr\"\u003e\n\u003cdiv\u003e\n\u003cb\u003eSafe Vials\u003c\/b\u003e Kisspeptin-10 is a high-purity, laboratory-grade synthetic 10-amino acid neuropeptide representing the minimal C-terminal bioactive fragment of the endogenous \u003ci\u003eKISS1\u003c\/i\u003e gene product (metastin). It serves as a primary, functional molecular probe to investigate kisspeptin-mediated signaling independently of full-length or precursor peptides.\u003c\/div\u003e\n\u003cbr\u003e\n\u003cdiv\u003eWithin cellular and neuroendocrine research systems, \u003cb\u003eSafe Vials\u003c\/b\u003e Kisspeptin-10 acts as a high-affinity agonist for the KISS1 receptor (\u003cem\u003e\u003cstrong\u003eKISS1R \/ GPR54\u003c\/strong\u003e\u003c\/em\u003e), a G-protein-coupled receptor predominantly expressed on hypothalamic gonadotropin-releasing hormone (\u003cem\u003e\u003cstrong\u003eGnRH\u003c\/strong\u003e\u003c\/em\u003e) neurons. It is widely utilized in scientific studies investigating the hypothalamic-pituitary-gonadal (\u003cem\u003e\u003cstrong\u003eHPG\u003c\/strong\u003e\u003c\/em\u003e) axis, gonadotropin secretion kinetics (\u003cem\u003e\u003cstrong\u003eLH \u003c\/strong\u003e\u003c\/em\u003eand \u003cem\u003e\u003cstrong\u003eFSH \u003c\/strong\u003e\u003c\/em\u003erelease), and reproductive endocrine signaling. Every lot is independently third-party tested and HPLC-verified (\u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e purity) to guarantee high experimental reproducibility.\u003c\/div\u003e\n\u003cbr\u003e\u003chr\u003e\n\u003ch2\u003eCompound Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eProduct Name:\u003c\/b\u003e Safe Vials Kisspeptin-10\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eClassification:\u003c\/b\u003e Synthetic Neuropeptide Fragment \/ \u003cem\u003eKISS1R\u003c\/em\u003e (\u003cem\u003e\u003cstrong\u003eGPR54\u003c\/strong\u003e\u003c\/em\u003e) Agonist\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eCAS Registry Number:\u003c\/b\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e374675-21-5\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Formula:\u003c\/b\u003e \u003cem\u003e\u003cstrong\u003eC₆₃H₈₃N₁₇O₁₄\u003c\/strong\u003e\u003c\/em\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Weight:\u003c\/b\u003e 1302.44 g\/mol\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSequence:\u003c\/b\u003e Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-\u003cspan\u003eNH₂\u003c\/span\u003e (10 Amino Acids, C-terminally amidated)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSynonyms:\u003c\/b\u003e Metastin (45–54), KiSS-1 derived decapeptide, KISS1R Ligand Fragment\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eResearch Highlights\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMinimal Bioactive Fragment:\u003c\/b\u003e Retains full binding affinity and potent agonist activity for the \u003cem\u003eKISS1R\u003c\/em\u003e (\u003cem\u003e\u003cstrong\u003eGPR54\u003c\/strong\u003e\u003c\/em\u003e) receptor while offering a compact sequence for controlled signaling assays.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eHPG Axis Upstream Regulation:\u003c\/b\u003e Acts as a standard reference peptide for probing hypothalamic \u003cem\u003eGnRH\u003c\/em\u003e pulse generator activity and downstream pituitary \u003cem\u003eLH\/FSH\u003c\/em\u003e secretion.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eG-Protein Coupled Receptor Dynamics:\u003c\/b\u003e Extensively applied in \u003ci\u003ein vitro\u003c\/i\u003e binding and functional assays to track \u003cem\u003eGαq\/11\u003c\/em\u003e-coupled intracellular calcium mobilization.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePubertal \u0026amp; Reproductive Model Standard:\u003c\/b\u003e Serves as a fundamental tool in neuroendocrine models evaluating central reproductive maturation, feedback loops, and fertility pathways.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eC-Terminal Amidation Stability:\u003c\/b\u003e Features a hydrophobic, amidated C-terminus essential for receptor engagement and structural stabilization against exopeptidase cleavage in research media.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eAnalytical Purity Verification:\u003c\/b\u003e Fully verified via third-party HPLC testing (\u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e purity) to ensure batch-to-batch consistency and accurate quantitative assay design.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePhysical Form:\u003c\/b\u003e Solid lyophilized powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eVisual Appearance:\u003c\/b\u003e Fine white to off-white cake\/powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePurity Level:\u003c\/b\u003e \u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e (HPLC Verified)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSolubility:\u003c\/b\u003e Readily soluble in sterile water or buffered aqueous solutions\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\u003cb\u003eStorage Requirements:\u003c\/b\u003e\u003c\/div\u003e\n\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eUnopened (Lyophilized):\u003c\/i\u003e Keep tightly sealed, desiccated, and stored at \u003cb\u003e-20°C\u003c\/b\u003e for long-term preservation (or \u003cb\u003e2–8°C\u003c\/b\u003e for short-term handling). Protect from light exposure.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eReconstituted Solution:\u003c\/i\u003e Store under refrigeration at \u003cb\u003e2°C – 8°C\u003c\/b\u003e. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eUsage Disclaimer:\u003c\/b\u003e Strictly for \u003ci\u003eIn Vitro\u003c\/i\u003e Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Safe Vials","offers":[{"title":"5mg","offer_id":57921590886782,"sku":null,"price":86.0,"currency_code":"CAD","in_stock":true},{"title":"10mg","offer_id":57921590919550,"sku":null,"price":96.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/9109\/9518\/files\/KissPeptin-10_5mg.png?v=1787794444","url":"https:\/\/safevials.com\/products\/kisspeptin-10","provider":"Safe Vials","version":"1.0","type":"link"}