{"product_id":"ss-31-50mg","title":"SS-31 50mg","description":"\u003cdiv class=\"markdown markdown-main-panel md-content enable-updated-hr-color force-compact-layout stronger tutor-markdown-rendering\" id=\"model-response-message-contentr_7d9ccf2353a7098f\" dir=\"ltr\"\u003e\n\u003cdiv\u003e\n\u003cb\u003eSafe Vials\u003c\/b\u003e SS-31 (Elamipretide) is a high-purity, laboratory-grade synthetic tetrapeptide engineered with an alternating cationic-aromatic structural motif \u003cem\u003e\u003cstrong\u003e(D-Arg-Dmt-Lys-Phe-NH₂).\u003c\/strong\u003e\u003c\/em\u003e This unique sequence allows the peptide to penetrate cellular membranes and accumulate in the inner mitochondrial membrane independently of mitochondrial membrane potential \u003cem\u003e\u003cstrong\u003e(ΔΨₘ).\u003c\/strong\u003e\u003c\/em\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003cdiv\u003eOnce localized to the inner membrane, \u003cb\u003eSafe Vials\u003c\/b\u003e SS-31 selectively associates with cardiolipin, the signature phospholipid essential for maintaining mitochondrial cristae structure and organizing respiratory chain supercomplexes. By stabilizing cardiolipin microdomains, SS-31 serves as a fundamental reference compound for investigating mitochondrial electron transport efficiency, reduction of reactive oxygen species (ROS) generation, and mechanisms of age-related cellular bioenergetic decline. Every batch is independently third-party tested and HPLC-verified (\u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e purity) to ensure maximum analytical consistency across study protocols.\u003c\/div\u003e\n\u003cbr\u003e\u003chr\u003e\n\u003ch2\u003eCompound Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eProduct Name:\u003c\/b\u003e Safe Vials SS-31\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eClassification:\u003c\/b\u003e Mitochondria-Targeting Tetrapeptide \/ Cardiolipin Stabilizer\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eCAS Registry Number:\u003c\/b\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e736992-21-5\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Formula:\u003c\/b\u003e \u003cem\u003e\u003cstrong\u003eC₃₂H₄₉N₉O₅\u003c\/strong\u003e\u003c\/em\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Weight:\u003c\/b\u003e 639.79 g\/mol\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSequence:\u003c\/b\u003e D-Arg-Dmt-Lys-Phe-\u003cspan\u003eNH₂\u003c\/span\u003e (4 Amino Acids, C-terminally amidated; \u003cspan\u003eDmt = 2',6'-dimethyl-L-tyrosine\u003c\/span\u003e)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSynonyms:\u003c\/b\u003e Elamipretide, MTP-131, Bendavia, Szeto-Schiller 31\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eResearch Highlights\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSelective Cardiolipin Binding:\u003c\/b\u003e Specifically associates with cardiolipin in the inner mitochondrial membrane, providing a targeted molecular tool for probing lipid-protein interactions.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePotential-Independent Uptake:\u003c\/b\u003e Unlike traditional lipophilic cationic probes, SS-31 accumulates within inner mitochondrial membranes without relying on membrane potential.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eElectron Transport \u0026amp; Supercomplex Organization:\u003c\/b\u003e Studied for its role in supporting cristae architecture and optimizing respiratory chain supercomplexes to examine ATP generation dynamics.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMitochondrial Redox Balance:\u003c\/b\u003e Serves as a standard reference peptide in cellular stress models to track reactive oxygen species (ROS) mitigation and oxidative stress pathways.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eCristae Architecture Research:\u003c\/b\u003e Widely utilized in models of age-related mitochondrial dysfunction to observe structural preservation of inner membrane curvature.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eAnalytical Purity Verification:\u003c\/b\u003e Fully verified via third-party HPLC testing (\u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e purity) to guarantee batch-to-batch reliability and consistent reconstitution.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePhysical Form:\u003c\/b\u003e Solid lyophilized powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eVisual Appearance:\u003c\/b\u003e Fine white to off-white cake\/powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePurity Level:\u003c\/b\u003e \u003cem\u003e\u003cstrong\u003e≥ 99%\u003c\/strong\u003e\u003c\/em\u003e (HPLC Verified)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSolubility:\u003c\/b\u003e Readily soluble in sterile water or bacteriostatic water\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\u003cb\u003eStorage Requirements:\u003c\/b\u003e\u003c\/div\u003e\n\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eUnopened (Lyophilized):\u003c\/i\u003e Keep tightly sealed and dry at \u003cb\u003e-20°C\u003c\/b\u003e for long-term storage (or \u003cb\u003e2–8°C\u003c\/b\u003e for short-term handling). Protect from light exposure and moisture.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eReconstituted Solution:\u003c\/i\u003e Store under refrigeration at \u003cb\u003e2°C – 8°C\u003c\/b\u003e. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eUsage Disclaimer:\u003c\/b\u003e Strictly for \u003ci\u003eIn Vitro\u003c\/i\u003e Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Safe Vials","offers":[{"title":"Default Title","offer_id":57898794582398,"sku":null,"price":254.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/9109\/9518\/files\/SS-31_50mg.png?v=1787371846","url":"https:\/\/safevials.com\/products\/ss-31-50mg","provider":"Safe Vials","version":"1.0","type":"link"}