{"product_id":"tesamorelin","title":"Tesamorelin","description":"\u003cdiv class=\"markdown markdown-main-panel md-content enable-updated-hr-color force-compact-layout stronger tutor-markdown-rendering\" id=\"model-response-message-contentr_3b99b89ed387e59a\" dir=\"ltr\"\u003e\n\u003cdiv\u003e\n\u003cb\u003eSafe Vials\u003c\/b\u003e Tesamorelin is a laboratory-grade, synthetic 44-amino acid growth hormone-releasing hormone (GHRH) analog engineered with an N-terminal trans-3-hexenoyl modification. This structural alteration substantially increases enzymatic stability by resisting cleavage by dipeptidyl peptidase-4 (DPP-4), extending its functional half-life relative to native, unmodified GHRH(1–44).\u003c\/div\u003e\n\u003cbr\u003e\n\u003cdiv\u003eBy selectively binding to pituitary GHRH receptors, \u003cb\u003eSafe Vials\u003c\/b\u003e Tesamorelin stimulates the natural, pulsatile secretion of endogenous growth hormone rather than introducing exogenous somatotropin. This makes it an invaluable reference standard for studies evaluating the hypothalamic-pituitary-somatotropic axis, hepatic IGF-1 transcription, and visceral adipose tissue dynamics. Every lot is co-analyzed and HPLC-verified (\u003cstrong\u003e≥ 98%\u003c\/strong\u003e purity) to guarantee high batch-to-batch reproducibility across long-term research protocols.\u003c\/div\u003e\n\u003cbr\u003e\u003chr\u003e\n\u003ch2\u003eCompound Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eProduct Name:\u003c\/b\u003e Safe Vials Tesamorelin\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eClassification:\u003c\/b\u003e Growth Hormone-Releasing Hormone (GHRH) Analog \/ Secretagogue\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eCAS Registry Number:\u003c\/b\u003e 218949-48-5\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Formula:\u003c\/b\u003e \u003cstrong\u003eC₃₆₆H₃₆₆N₇₂O₆₇S\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eMolecular Weight:\u003c\/b\u003e 5135.83 g\/mol\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cspan class=\"citation-17\"\u003e\u003c\/span\u003e\u003cb\u003e\u003cspan class=\"citation-17\"\u003eSequence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-17 citation-end-17\"\u003e Trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-\u003cstrong\u003eNH₂\u003c\/strong\u003e\u003c\/span\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSynonyms:\u003c\/b\u003e TH9507, Egrifta, Trans-3-hexenoyl-GHRH(1–44)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eResearch Highlights\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eDPP-4 Enzymatic Resistance:\u003c\/b\u003e The addition of an N-terminal trans-3-hexenoyl group protects against rapid cleavage by dipeptidyl peptidase-4, significantly extending functional half-life in study models.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePreserved Pulsatile GH Dynamics:\u003c\/b\u003e Stimulates natural pituitary growth hormone synthesis and release, maintaining physiological feedback loops and pulsatile secretion patterns.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eVisceral Adipose Tissue Signaling:\u003c\/b\u003e Widely referenced in metabolic literature examining lipolytic signaling mechanisms, visceral fat reduction pathways, and lipid transport.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eGH–IGF-1 Axis Modulation:\u003c\/b\u003e Serves as a standard baseline compound for investigating downstream insulin-like growth factor-1 (IGF-1) elevation and hepatic gene expression.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eHigh Analytical Purity:\u003c\/b\u003e Every lot undergoes third-party HPLC verification to ensure \u003cstrong\u003e≥ 98%\u003c\/strong\u003e purity for reliable \u003ci\u003ein vitro\u003c\/i\u003e and cell culture assays.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePhysical Form:\u003c\/b\u003e Lyophilized solid powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eVisual Appearance:\u003c\/b\u003e White to off-white cake\/powder\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003ePurity Level:\u003c\/b\u003e \u003cstrong\u003e≥ 98%\u003c\/strong\u003e (HPLC Verified)\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eSolubility:\u003c\/b\u003e Readily soluble in sterile water or bacteriostatic water\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\u003cb\u003eStorage Requirements:\u003c\/b\u003e\u003c\/div\u003e\n\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eUnopened (Lyophilized):\u003c\/i\u003e Keep sealed and dry at \u003cb\u003e-20°C\u003c\/b\u003e for long-term storage (or \u003cb\u003e2–8°C\u003c\/b\u003e for short-term handling). Protect from light and atmospheric moisture.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003ci\u003eReconstituted Solution:\u003c\/i\u003e Store under refrigeration at \u003cb\u003e2°C – 8°C\u003c\/b\u003e. Aliquot working stock solutions to prevent repeated freeze-thaw degradation.\u003c\/div\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cdiv\u003e\n\u003cb\u003eUsage Disclaimer:\u003c\/b\u003e Strictly for \u003ci\u003eIn Vitro\u003c\/i\u003e Laboratory Research and Development Use Only. Not for human consumption, therapeutic, or diagnostic applications.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Safe Vials","offers":[{"title":"10mg","offer_id":57863801274750,"sku":null,"price":109.0,"currency_code":"CAD","in_stock":true},{"title":"20mg","offer_id":57863801307518,"sku":null,"price":182.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/9109\/9518\/files\/Tesamorelin_10mg.png?v=1787137471","url":"https:\/\/safevials.com\/products\/tesamorelin","provider":"Safe Vials","version":"1.0","type":"link"}