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Safe Vials

KPV 10mg

KPV 10mg

+99% Purity Third-Party Tested COA Available
$73.00
$73.00
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Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

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Description

Safe Vials KPV is a high-purity, laboratory-grade synthetic tripeptide corresponding to the C-terminal amino acid sequence (residues 11–13) of alpha-melanocyte-stimulating hormone (α-MSH). While full-length α-MSH engages multiple melanocortin receptors that induce pigmentary changes alongside immune modulation, KPV retains the parent hormone's potent anti-inflammatory signaling properties without activating pigment-producing pathways.

By eliminating melanogenic activity, Safe Vials KPV allows researchers to isolate and study anti-inflammatory mechanisms in a clean experimental environment. Primary investigation centers on its role in suppressing nuclear factor kappa B (NF-κB) translocation, reducing pro-inflammatory cytokine expression, and reinforcing epithelial tight-junction integrity in gut and dermal tissue models. Every lot is independently third-party tested and HPLC-verified (≥ 99% purity) to ensure reproducible quantitative performance.

Compound Information

  • Product Name: Safe Vials KPV

  • Classification: Anti-Inflammatory Tripeptide / $\alpha\text{-MSH}$ Fragment

  • CAS Registry Number: 67727-97-3

  • Molecular Formula: C₁₆H₃₀N₄O₄

  • Molecular Weight: 342.44 g/mol

  • Sequence: Lys-Pro-Val (3 Amino Acids, C-terminal fragment of α-MSH(11–13))

  • Synonyms: α-MSH(11–13), Lysine-Proline-Valine

Research Highlights

  • Targeted Anti-Inflammatory Signaling: Preserves the core immunomodulatory signaling of native α-MSH(11–13) in a compact three-amino-acid sequence.

  • Non-Pigmentary Pathway Isolation: Operates without activating pigmentary melanocortin receptors, providing a clean probe for inflammatory research without pigment confounding.

  • NF-κB Pathway Suppression: Extensively studied in cell culture assays for inhibiting NF-κB nuclear translocation and downstream inflammatory cascades.

  • Epithelial Barrier Integrity: Serves as a standard reference compound in mucosal, gastrointestinal, and dermal tissue models to track tight-junction preservation.

  • Cytokine Modulation: Applied in stimulated cell protocols to evaluate the down-regulation of pro-inflammatory cytokines such as TNF-α and IL-6.

  • Analytical Purity Verification: Fully verified via third-party HPLC testing (≥ 99% purity) to maintain batch-to-batch consistency across experimental replicates.

Product Specifications

  • Physical Form: Solid lyophilized powder

  • Visual Appearance: Fine white to off-white cake/powder

  • Purity Level: ≥ 99% (HPLC Verified)

  • Solubility: Soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Keep tightly sealed and dry at -20°C for long-term storage (or 2–8°C for short-term handling). Protect from light and atmospheric moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions into single-use volumes to prevent structural degradation from repeated freeze-thaw cycles.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.