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Safe Vials

Melanotan 2 10mg

Melanotan 2 10mg

+99% Purity Third-Party Tested COA Available
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Regular price $66.00
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Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

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Description

Safe Vials Melanotan 2 (MT-2) is a high-purity, laboratory-grade synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). Originally developed in university research settings as a stable probe for the melanocortin receptor system, its defining structural feature is a lactam bridge between its Asp and Lys residues. This structural modification locks the peptide into a constrained ring conformation, conferring significantly higher receptor affinity and metabolic stability against enzymatic degradation compared to native linear α-MSH.

As a non-selective agonist, Safe Vials Melanotan 2 binds across multiple melanocortin receptor subtypes, including MC1R/MC3R/MC4R, and MC5R. This broad activity profile makes it a foundational reference compound across diverse research fields—from investigating MC1R-mediated melanocyte activation and eumelanin synthesis to probing central MC4R-driven energy balance pathways. Every lot is independently third-party tested and HPLC-verified (≥ 99% purity) to ensure maximum consistency across long-term protocols.


Compound Information

  • Product Name: Safe Vials Melanotan 2

  • Classification: Cyclic Heptapeptide / Non-Selective Melanocortin Agonist (α-MSH Analog)

  • CAS Registry Number: 121062-08-6

  • Molecular Formula: C₅₀H₆₉N₁₅O₉

  • Molecular Weight: 1024.18 g/mol

  • Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ (7 Amino Acids, lactam-bridged)

  • Synonyms: MT-2, MT-II, Melanotan II


Research Highlights

  • Cyclic Lactam Architecture: The Asp–Lys lactam ring provides exceptional structural rigidity, protecting the peptide against rapid enzymatic cleavage and ensuring prolonged binding interactions.

  • Broad-Spectrum Agonism: Engages MC1R, MC3R, MC4R, and MC5R receptors, serving as an essential pan-melanocortin benchmark ligand.

  • Melanogenesis & Pigmentation Models: Drives MC1R pathway activation to induce eumelanin synthesis in melanocyte culture models.

  • Central MC4R Signaling Probe: Widely utilized in neuroendocrine studies examining central nervous system control over energy regulation and behavioral responses.

  • Comparative Research Standard: Serves as the primary reference compound against which novel, subtype-selective melanocortin agonists are benchmarked.

  • Analytical Purity Verification: Fully verified via third-party HPLC testing (≥ 99% purity) to ensure particulate-free, reproducible experimental outcomes.


Product Specifications

  • Physical Form: Solid lyophilized powder

  • Visual Appearance: Fine white to off-white cake/powder

  • Purity Level: ≥ 99% (HPLC Verified)

  • Solubility: Soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Store tightly sealed and dry at -20°C for long-term preservation (or 2–8°C for short-term handling). Protect from light and moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.