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Safe Vials

PT 141 10mg

PT 141 10mg

+99% Purity Third-Party Tested COA Available
$55.00
$55.00
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Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

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Description

Safe Vials PT-141 (Bremelanotide) is a high-purity, laboratory-grade synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). Derived structurally from Melanotan II, PT-141 features a constrained cyclic lactam architecture that confers superior metabolic stability against enzymatic degradation relative to linear melanocortin analogs while preserving strong receptor affinity.

Operating as an agonist across multiple melanocortin receptor subtypes, research surrounding Safe Vials PT-141 primarily focuses on central nervous system engagement—specifically targeting MC4R and MC3R pathways. Because it acts down-stream via central neural signaling rather than vascular pathways, PT-141 serves as an essential reference compound for mapping melanocortin pathway activation, receptor selectivity, and central neuroendocrine responses. Every lot is independently third-party tested and HPLC-verified (≥ 99% purity) to provide researchers with a highly reproducible, contaminant-free standard.

Compound Information

  • Product Name: Safe Vials PT-141

  • Classification: Melanocortin Receptor Agonist / Cyclic Peptide

  • CAS Registry Number: 189691-06-3

  • Molecular Formula: C₅₀H₆₈N₁₄O₁₀

  • Molecular Weight: 1025.16 g/mol

  • Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (7 Amino Acids)

  • Synonyms: Bremelanotide, Vyleesi, Melanotan II Metabolite

Research Highlights

  • Cyclic Lactam Stability: The constrained ring structure resists enzymatic degradation significantly better than linear sequences, ensuring high stability during experimental assays.

  • Central MC4R Pathway Engagement: Serves as a key biological probe for investigating central nervous system melanocortin-4 receptor (MC4R) signaling dynamics.

  • Broad Receptor Subtype Activity: Acts as an agonist across several melanocortin receptor subtypes, making it a valuable baseline comparator in receptor binding and selectivity assays.

  • Structural Analog Reference: Shares a cyclic lactam core with Melanotan II, providing a clear reference point for comparative structural studies within the melanocortin family.

  • Non-Vascular Mechanism: Enables researchers to study central neuroendocrine responses independent of direct vascular smooth muscle mechanisms.

  • Analytical Purity Verification: Independently verified via HPLC to confirm ≥ 99% purity for batch-to-batch consistency in quantitative laboratory protocols.

Product Specifications

  • Physical Form: Solid lyophilized powder

  • Visual Appearance: Fine white to off-white powder

  • Purity Level: ≥ 99% (HPLC Verified)

  • Solubility: Readily soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Keep tightly sealed and dry at -20°C for long-term storage (or 2–8°C for short-term handling). Protect from light and moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.