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Safe Vials

Semax 10mg

Semax 10mg

+99% Purity Third-Party Tested COA Available
$56.00
$56.00
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Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

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Description

Safe Vials Semax is a high-purity, laboratory-grade synthetic heptapeptide combining the active adrenocorticotropic hormone fragment ACTH(4–7) with a C-terminal Pro-Gly-Pro tripeptide extension. Originally developed as a stabilized neuropeptide analog, Semax incorporates this specific C-terminal tail to slow down enzymatic breakdown by proteases while completely eliminating the corticotropic (adrenal-stimulating) activity characteristic of full-length ACTH.

By removing adrenal signaling confounds, Safe Vials Semax enables researchers to isolate and investigate central neurotropic processes. Research primarily focuses on its capacity to upregulate brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), modulate dopaminergic and serotonergic turnover, and protect neuronal tissue in cerebral ischemia models. Every batch is independently third-party tested and HPLC-verified (≥ 99% purity) to ensure maximum experimental stability and reproducibility.

Compound Information

  • Product Name: Safe Vials Semax

  • Classification: Neuropeptide / ACTH(4–7) Fragment Analog

  • CAS Registry Number: 80714-61-0

  • Molecular Formula: C₃₇H₅₁N₉O₁₀S

  • Molecular Weight: 813.92 g/mol

  • Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (7 Amino Acids)

  • Synonyms: ACTH(4–7)-Pro-Gly-Pro, MEHFPGP

Research Highlights

  • BDNF & NGF Upregulation: Widely studied for driving neurotrophic factor expression in cortical and hippocampal tissue assays to support synaptic plasticity research.

  • Absence of Corticotropic Activity: Lacks the adrenal-stimulating properties of native ACTH, permitting clean evaluation of central nervous system pathways without HPA-axis interference.

  • Proteolytic Cleavage Resistance: The C-terminal Pro-Gly-Pro addition significantly extends peptide half-life in working media compared to unmodified ACTH(4–7).

  • Ischemia & Neuroprotection Models: Frequently cited in preclinical research investigating cellular stress responses and tissue survival under reduced cerebral perfusion.

  • Neurotransmitter Systems Modulation: Used as a reference standard to track turnover rates within dopaminergic and serotonergic pathways.

  • Analytical Purity Verification: Fully verified via third-party HPLC testing (≥ 99% purity) to ensure reliable, particle-free reconstitution across long study timelines.

Product Specifications

  • Physical Form: Solid lyophilized powder

  • Visual Appearance: Fine white to off-white cake/powder

  • Purity Level: ≥ 99% (HPLC Verified)

  • Solubility: Readily soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Keep tightly sealed and dry at -20°C for long-term storage (or 2–8°C for short-term handling). Protect from direct light and moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.