1 1

Safe Vials

SS-31 50mg

SS-31 50mg

+99% Purity Third-Party Tested COA Available
$254.00
$254.00
Sale Sold out
Shipping calculated at checkout.
SSL Secured
Secure Checkout
Guaranteed Delivery
CUSTOMER CARE
Talk to a person WHATSAPP CHAT →

Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

View full details

Description

Safe Vials SS-31 (Elamipretide) is a high-purity, laboratory-grade synthetic tetrapeptide engineered with an alternating cationic-aromatic structural motif (D-Arg-Dmt-Lys-Phe-NH₂). This unique sequence allows the peptide to penetrate cellular membranes and accumulate in the inner mitochondrial membrane independently of mitochondrial membrane potential (ΔΨₘ).

Once localized to the inner membrane, Safe Vials SS-31 selectively associates with cardiolipin, the signature phospholipid essential for maintaining mitochondrial cristae structure and organizing respiratory chain supercomplexes. By stabilizing cardiolipin microdomains, SS-31 serves as a fundamental reference compound for investigating mitochondrial electron transport efficiency, reduction of reactive oxygen species (ROS) generation, and mechanisms of age-related cellular bioenergetic decline. Every batch is independently third-party tested and HPLC-verified (≥ 99% purity) to ensure maximum analytical consistency across study protocols.

Compound Information

  • Product Name: Safe Vials SS-31

  • Classification: Mitochondria-Targeting Tetrapeptide / Cardiolipin Stabilizer

  • CAS Registry Number: 736992-21-5

  • Molecular Formula: C₃₂H₄₉N₉O₅

  • Molecular Weight: 639.79 g/mol

  • Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (4 Amino Acids, C-terminally amidated; Dmt = 2',6'-dimethyl-L-tyrosine)

  • Synonyms: Elamipretide, MTP-131, Bendavia, Szeto-Schiller 31

Research Highlights

  • Selective Cardiolipin Binding: Specifically associates with cardiolipin in the inner mitochondrial membrane, providing a targeted molecular tool for probing lipid-protein interactions.

  • Potential-Independent Uptake: Unlike traditional lipophilic cationic probes, SS-31 accumulates within inner mitochondrial membranes without relying on membrane potential.

  • Electron Transport & Supercomplex Organization: Studied for its role in supporting cristae architecture and optimizing respiratory chain supercomplexes to examine ATP generation dynamics.

  • Mitochondrial Redox Balance: Serves as a standard reference peptide in cellular stress models to track reactive oxygen species (ROS) mitigation and oxidative stress pathways.

  • Cristae Architecture Research: Widely utilized in models of age-related mitochondrial dysfunction to observe structural preservation of inner membrane curvature.

  • Analytical Purity Verification: Fully verified via third-party HPLC testing (≥ 99% purity) to guarantee batch-to-batch reliability and consistent reconstitution.

Product Specifications

  • Physical Form: Solid lyophilized powder

  • Visual Appearance: Fine white to off-white cake/powder

  • Purity Level: ≥ 99% (HPLC Verified)

  • Solubility: Readily soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Keep tightly sealed and dry at -20°C for long-term storage (or 2–8°C for short-term handling). Protect from light exposure and moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions to prevent structural degradation from repeated freeze-thaw cycles.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.