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Safe Vials

Tesamorelin

Tesamorelin

+99% Purity Third-Party Tested COA Available
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$109.00
$109.00
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Strictly for laboratory research and development use only. Not for human, therapeutic, or diagnostic applications.

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Description

Safe Vials Tesamorelin is a laboratory-grade, synthetic 44-amino acid growth hormone-releasing hormone (GHRH) analog engineered with an N-terminal trans-3-hexenoyl modification. This structural alteration substantially increases enzymatic stability by resisting cleavage by dipeptidyl peptidase-4 (DPP-4), extending its functional half-life relative to native, unmodified GHRH(1–44).

By selectively binding to pituitary GHRH receptors, Safe Vials Tesamorelin stimulates the natural, pulsatile secretion of endogenous growth hormone rather than introducing exogenous somatotropin. This makes it an invaluable reference standard for studies evaluating the hypothalamic-pituitary-somatotropic axis, hepatic IGF-1 transcription, and visceral adipose tissue dynamics. Every lot is co-analyzed and HPLC-verified (≥ 98% purity) to guarantee high batch-to-batch reproducibility across long-term research protocols.

Compound Information

  • Product Name: Safe Vials Tesamorelin

  • Classification: Growth Hormone-Releasing Hormone (GHRH) Analog / Secretagogue

  • CAS Registry Number: 218949-48-5

  • Molecular Formula: C₃₆₆H₃₆₆N₇₂O₆₇S

  • Molecular Weight: 5135.83 g/mol

  • Sequence: Trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂

  • Synonyms: TH9507, Egrifta, Trans-3-hexenoyl-GHRH(1–44)

Research Highlights

  • DPP-4 Enzymatic Resistance: The addition of an N-terminal trans-3-hexenoyl group protects against rapid cleavage by dipeptidyl peptidase-4, significantly extending functional half-life in study models.

  • Preserved Pulsatile GH Dynamics: Stimulates natural pituitary growth hormone synthesis and release, maintaining physiological feedback loops and pulsatile secretion patterns.

  • Visceral Adipose Tissue Signaling: Widely referenced in metabolic literature examining lipolytic signaling mechanisms, visceral fat reduction pathways, and lipid transport.

  • GH–IGF-1 Axis Modulation: Serves as a standard baseline compound for investigating downstream insulin-like growth factor-1 (IGF-1) elevation and hepatic gene expression.

  • High Analytical Purity: Every lot undergoes third-party HPLC verification to ensure ≥ 98% purity for reliable in vitro and cell culture assays.

Product Specifications

  • Physical Form: Lyophilized solid powder

  • Visual Appearance: White to off-white cake/powder

  • Purity Level: ≥ 98% (HPLC Verified)

  • Solubility: Readily soluble in sterile water or bacteriostatic water

  • Storage Requirements:

    • Unopened (Lyophilized): Keep sealed and dry at -20°C for long-term storage (or 2–8°C for short-term handling). Protect from light and atmospheric moisture.

    • Reconstituted Solution: Store under refrigeration at 2°C – 8°C. Aliquot working stock solutions to prevent repeated freeze-thaw degradation.

  • Usage Disclaimer: Strictly for In Vitro Laboratory Research and Development Use Only. Not for human consumption, therapeutic, or diagnostic applications.

Research Studies

Frequently Asked Questions

Are your peptides lab tested?

Yes, all our products are tested by third-party laboratories.
COAs are available per batch.

Why is my peptide not dissolving properly?

Some peptides dissolve slower than others.
Using bacteriostatic water or first adding a small amount of acetic acid can improve dissolution.

Why does my peptide look different?

Peptides can appear as powder, flakes, or a solid “puck”.
This is normal and caused by the freeze-drying process — it does not affect quality.

How should I store peptides?

  • Long-term: freezer (-18 to -20°C)
  • After mixing: refrigerator (2–8°C)
  • Always keep away from light and heat

Are your products for human consumption?

No. All products are sold strictly for research purposes only.
They are not intended for human or animal use.

Do you offer refunds or reships?

We handle issues case-by-case.
If there is a problem with your order (damage, delivery issue), we will always work towards a solution including reshipment where appropriate.